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Contrastive Discovery: Open-Ended Scientific Discovery over Competing Explanations

arXiv · 2026-11-10 · buzz 80

LLM agents are increasingly used for open-ended, data-driven scientific discovery, yet most of them evaluate hypotheses pointwise, testing an empirical claim $h$ only against its complement $\neg h$. When evidence rejects $h$, the agent learns that one explanation is unlikely but not which alternative the evidence supports. To recover that alternative, we introduce Contrastive Discovery, which rep

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